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Magnetic resonance therapy : ウィキペディア英語版
Magnetic resonance therapy
Magnetic resonance therapy is a treatment method based on the physical principle of magnetic resonance. It aims to activate reparative processes in specific cells and tissues. So far, there is no major clinical trial supporting the effectiveness of the method.〔W. Kullich, H. Schwann, J. Walcher, K. Machreich (2006). "The effect of MBST with complex 3-dimensional electromagnetic nuclear resonance fields on patients with low back pain." ''Journal of Back and Musculoskeletal Rehabilitation'', 19:79-87 (abstract )〕〔W. Kullich, M. Außerwinkler (2008). "Functional improvement in finger joint osteoarthritis with therapeutic use of nuclear magnetic resonance." ''Orthopedic Practice''. S. 287-290 (poster )〕〔Temiz-Artmann A, Linder P, Kayser, Digel I, Artmann GM, Lücker P (2005). (PMID 16179956 "NMR in vitro effects on proliferation, apoptosis, and viability of human chondrocytes and osteoblasts. Methods Find" ), ''Exp Clin Pharmacol'' 27:391-4〕〔A. Levers, M. Staat, W. van Laack (2011). "Analysis of the Long-term Effect of the Nuclear Magnetic Resonance Therapy on Gonarthrosis"s Special edition from ''Orthopedic Practice'' 11 (abstract )〕〔Jansen H, Frey SP, Paletta J, Meffert RH. (2011). "Effects of low-energy NMR on posttraumatic osteoarthritis: observations in a rabbit model", ''Arch Orthop Trauma Surg.'' (6):863-8. PMID 21063883〕
The therapy is used predominantly by practitioners for the complementary treatment of painful degenerate or pathological modifications to the musculoskeletal system. Magnetic resonance therapy is carried out internationally in clinical practices and rehabilitation facilities. It is also supported by research establishments, e.g. the Ludwig-Boltzmann Institute in Saalfelden, Austria.
The therapy can be considered as alternative medicine as it is not approved by conventional medicine. The field generated is approximately 10,000 weaker than a diagnostic MRI,〔http://www.mbst.de/en/faq/〕 standard modern MRI machines being around 1.5 Tesla.
==Functional principle==
(詳細はnuclei to a magnetic field causes them to arrange themselves in relation to the field. They spin around their own axis (precession) and the speed is given by the Larmor frequence \omega.
After the nuclei have been aligned along the field they are be exposed to a radio magnetic pulse. If the precession frequence is the same as the frequence of the applied radio wave, the nuclei will absorb energy from the radio waves. Hence, nuclear magnetic resonance is the selective absorption of specific frequences of radio waves by atomic nuclei in a magnetic field.
The spin vectors will then start to move in phase and fall back in equilibrium as soon as the radio wave is switched off. The absorbed energy will be transmitted as radiation.
This process gives information about the molecular structure of the material and is applied in medicine to obtain images by observing the magnetic moments of hydrogen nuclei in the body (magnetic resonance imaging).〔Loeffler W, Oppelt A (1981). "Physical principles of NMR tomography PMID 7346283", ''Eur J Radiol.'' Nov;1(4):338-44.〕
Given that hydrogen nuclei respond differently in various biological tissue structures, it is aimed by practitioners of the method to take advantage of this process in magnetic resonance therapy.〔D. Krpan (2011) Nuclear Magnetic Resonance Therapy. The new possible of osteoarthritis and osteoporosis treatment. Balneoclimatologia . Volume 35 Broj 3〕
The technical specific feature of the method is that the physical technique of 'adiabatic fast passage' is used to generate the magnetic resonant spin activation.〔E. Kupce (2001) Applications of adiabatic pulses in biomolecular nuclear magnetic resonance. Methods Enzymol. 338:82-111 PMID 11460562〕〔A. Abragam (1961). The Principles of Nuclear Magnetism. International series of monographs on physics 32. Oxford University Press.〕
The condition of 'adiabatic fast passage' is given by:
( \frac \cdot \frac \ge \gamma B_0 ) \wedge ( \frac \cdot \frac \gg \frac )
Whereby B_1 is the magnetic excitation within the high frequency range and dB_0/dt is the rate of change of the magnetic excitation of the main field caused by the sweep field; \gamma is the gyromagnetic constant.
This condition assures that magnetic resonance is created despite small-or inhomogeneous magnetic fields.
The principle is patent-registered (e.g. U.S. Patent 7,524,276; EU-Patent EP 1 089 792 B1) and approved for medical devices in agreement with 93/42/EWG.

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